For clinical guidelines to be useful they need to be evidence-based, current and widely disseminated. These goals were difficult to achieve with printed guidelines. For the past 10 years, the guideline development community has focused on implementing digital systems to improve quality and uptake of clinical practice guidelines. Dynamic systems have been developed to assist with evidence synthesis, linking and updating of data as well as dissemination. Systematic reviews are now conceptualised as living systematic reviews that are regularly updated as soon as new key evidence emerges. This presentation gives an overview of digital guideline development initiatives and discusses achievements as well as challenges.